产品货号：
Z38492
中文名称：
HCK抗体
英文名称：
Anti-HCK Antibody (Clone#3D12E1)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HCK Antibody (Clone#3D12E1) |
| 指标别名 | HCK;hemopoietic cell kinase;JTK9;p59 HCK/p60 HCK;Tyrosine protein kinase HCK |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | HCK |
| 克隆号 | 3D12E1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Purified recombinant fragment of Hck expressed in E.Coli. |
| 计算分子量 | 60KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide,0.5% BSA,50% glycerol. |
| 纯化方式 | Affinity purification |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of innate immune responses,including neutrophil,monocyte,macrophage and mast cell functions,phagocytosis,cell survival and proliferation,cell adhesion and migration.Acts downstream of receptors that bind the Fc region of immunoglobulins,such as FCGR1A and FCGR2A,but also CSF3R,PLAUR,the receptors for IFNG,IL2,IL6 and IL8,and integrins,such as ITGB1 and ITGB2.During the phagocytic process,mediates mobilization of secretory lysosomes,degranulation,and activation of NADPH oxidase to bring about the respiratory burst.Plays a role in the release of inflammatory molecules.Promotes reorganization of the actin cytoskeleton and actin polymerization,formation of podosomes and cell protrusions.Inhibits TP73-mediated transcription activation and TP73-mediated apoptosis.Phosphorylates CBL in response to activation of immunoglobulin gamma Fc region receptors.Phosphorylates ADAM15,BCR,ELMO1,FCGR2A,GAB1,GAB2,RAPGEF1,STAT5B,TP73,VAV1 and WAS. |
| Uniprot ID | P08631 |
| 基因名全称 | Tyrosine-protein kinase HCK |
| 推荐稀释比 | WB,1:500～1:2000 IHC,1:200～1:1000 |
相关搜索：HCK抗体，HCK单抗，Anti-HCK Antibody (Clone#3D12E1)